At Laser Medicine, we take a science-led, integrative approach to fertility support, combining advanced metabolic health therapies with personalised care. In partnership with the Harley Street Fertility Clinic we offer Hyperbaric Oxygen Therapy for Fertility, and we the first IVF clinic in the UK to offer HBOT for Fertility in-house, under the expert supervision of the specialist IVF gynaecologist team.

HBOT for Fertility may be particularly relevant for people undergoing IVF, experiencing poor ovarian response, or seeking to optimise overall reproductive health alongside conventional fertility treatments. Hyperbaric Oxygen Therapy (HBOT) is emerging as a supportive therapy to improve reproductive health outcomes for men an women. By delivering high concentrations of oxygen under gentle pressure (1.3 – 1.5 ATA), HBOT for Fertility may help improve circulation, cellular energy production, tissue repair, and oxygen delivery to the testes, ovaries and endometrium — areas critical for healthy reproductive function.

We have selected the very best in Hyperbaric Oxygen Therapy equipment, hand assembled in Korea by Hue Light, and designed to high medical equipment specifications. Patients sit back and relax in a leather seated, air-conditioned Hyperbaric Oxygen Chamber, which many people say feels like a “First Class Airline Cabin”.

What HBOT for Fertility research reveals so far

Interest in HBOT for Fertlity as a supportive therapy has grown significantly in recent years. Hyperbaric Oxygen Therapy (HBOT) involves breathing concentrated oxygen inside a pressurised chamber, increasing the amount of oxygen dissolved within the blood and delivered to tissues throughout the body. Researchers are now investigating whether improved oxygenation may help support ovarian function, egg quality, embryo development, and endometrial health.

Emerging evidence suggests HBOT for Fertility may be particularly relevant for women experiencing poor ovarian response (POR) during IVF treatment. A 2025 pre-post cohort study found that HBOT significantly improved oocyte yield, fertilisation rates, and embryo quality in women undergoing fertility treatment. The researchers observed the greatest improvements after approximately 4–7 HBOT for Fertility sessions during ovarian stimulation. 

Earlier pilot research published in Fertility and Sterility also reported that HBOT for Fertility was well tolerated in women undergoing IVF and warranted further investigation as an adjunctive fertility therapy. Additional experimental studies have demonstrated that hyperbaric oxygen exposure may reduce follicular cell apoptosis, improve oocyte maturation, and support blastocyst development. 

A proposed mechanism behind these effects is improved oxygen delivery to reproductive tissues. Adequate oxygenation is important for mitochondrial energy production, cellular repair, blood vessel formation, and reducing oxidative stress within the ovaries and endometrium. Researchers have also suggested HBOT for Fertility may help improve endometrial receptivity and uterine blood flow, both of which are important factors in successful implantation. 

As leaders in Light Therapy for Fertility, the Laser Medicine HBOT for Fertility service is part of a broader integrative approach to Ovarian Rejuvenation and Reproductive Health. While research remains ongoing and HBOT should not be viewed as a standalone fertility treatment, the current evidence base is encouraging and continues to expand. We aim to make our own valuable contributions to the research field.

As with all fertility-related therapies, we assess suitability for HBOT for Fertility on an individual basis, with appropriately qualified fertility health professionals.

Clinical studies relating to Hyperbaric Oxygen for Fertility

Hyperbaric oxygen therapy improves oocyte yield and embryo quality in poor ovarian responders: a pre-post cohort study

HBOT significantly increased the number of oocytes, follicle output rate (FORT), follicle-to-oocyte index (FOI), two-pronuclear (2PN), available embryos, normal fertilization rate, and available embryos rate.

Hyperbaric oxygen therapy for male infertility: a systematic review and meta-analysis on improving sperm quality and fertility outcomes

A comprehensive literature search identified nine eligible studies, which were assessed for quality using the Jadad scale and analyzed for heterogeneity. The meta-analysis revealed significant improvements in sperm survival, density, morphology, normal sperm rates, and motility following hyperbaric oxygen therapy, with an increased clinical pregnancy rate.

Hyperbaric oxygen therapy and in vitro fertilization—a pilot study

Follicular fluid VEGF levels were higher in HBO treated women than in 5 control samples, with 2 out 5 patients achieving succesful pregancy, both with ongoing twin gestations.