Laser Medicine offers a comprehensive Ovarian Rejuvenation Programme (ORP) at our Harley Street Clinic, London, and is the first IVF clinic in London to provide Ovarian and Uterine PRP, Photobiomodulation Light Therapy and Hyperbaric Oxygen Therapy (HBOT) at the same location, all under one roof.

We have recently enhanced the Ovarian Rejuvenation Programme (ORP 2.0) with additional therapeutic options in a dedicated metabolic health facility known as BAHI Health Optimisation. The newly added BAHI Therapy for Fertility service includes Hyperbaric Oxygen Therapy for Fertility, Whole Body PBM Therapy, Hydrogen Inhalation and Wave Motion Vibration.

The Ovarian Rejuvenation Programme (ORP 2.0) combines a number of clinically proven protocols for the application of Low Level Laser / Red Light Therapy for Fertility, Ovarian / Uterine PRP and Hyperbaric Oxygen for Fertility treatments. The Ovarian Rejuvenation Programme (ORP 2.0) is suitable for people of all ages, especially over 35 years who have failed to conceive naturally or by IVF. The programme is also suitable for men with compromised gonad function and sperm quality.

What does the Ovarian Rejuvenation Programme (ORP 2.0) involve?

Building on protocols developed from our Low Level Laser Therapy for Fertility programme, the Ovarian Rejuvenation Programme (ORP) combines Ovarian and Uterine PRP carried out by expert fertility gynaecologists, Low Level Laser (Photobiomodulation Red Light Therapy) using advanced medical therapeutic laser equipment, and Hyperbaric Oxygen Therapy for Fertility.

The Ovarian Rejuvenation Programme is delivered under one roof in the pleasant surroundings of the Harley Street Fertility Clinic, a beautiful grade 2 listed building deep in the heart of London’s private medical district. The Ovarian Rejuvenation Programme (ORP 2.0) is a unique fertility offering, with no other IVF clinic within the UK offering a comprehensive set of Ovarian Rejuvenation Treatments in the same place.

Medical-led ovarian rejuvenation treatments

We tailor the Ovarian Rejuvenation Programme (ORP 2.0) for each person and / or for the couple involved, however as a general guide a programme would take place over 8 consecutive weeks and include the following course of treatments:

6 Red Light Photobiomodulation Therapy / LLLT sessions.
2 Ovarian PRP Treatments.
5 Hyperbaric Oxygen Therapy Treatments.
Programme delivered over an 8 week period:
1 PRP treatment is followed by 3 LLLT sessions at weekly intervals, and then repeated in the second consecutive month.
Hyperbaric Oxygen Therapies taken either at weekly intervals, or 2-3 per week in the lead up to an IVF retrieval or Frozen Egg Transfer.

How does Low Level Laser (LLLT) and Ovarian PRP work?

The Ovarian Rejuvenation Programme (ORP) combines Therapeutic Laser (PBM/Red Light) with Ovarian / Uterine PRP to promote good reproductive health and improve fertility outcomes.

LLLT for Ovarian Rejuvenation

Therapeutic Laser is a safe and effective adjunct to support ovarian rejuvenation. It is also known as Low Level Laser Therapy (LLLT) and Red Light Therapy (because of the wavelengths used within the Infrared / Near Infrared range (600-1,000nm)). Clinical studies have shown the effectiveness of using Red Light for Ovarian Rejuvenation, which benefits the reproductive system in the following ways:

Enhanced mitochondrial activity and ATP production.
Increased oxygenated blood flow.
Reduced inflammation and oxidative damage.
Softening of scar tissue and its release through the body’s waste system.
Promotion of tissue repair and energetic integrity.

Clinical case studies for the use of LLLT / Photobiomodulation Therapy, published in PubMed:
The Efficacy of Multiwavelength Red and Near-Infrared Transdermal Photobiomodulation Light Therapy in Enhancing Female Fertility Outcomes and Improving Reproductive Health: A Prospective Case Series with 9-Month Follow-Up (Phypers et al 2024).

Photobiomodulation in Complex Female Infertility Profile: A Case Report with 12-Month Follow-Up and Review of Current Mechanism in Reproductive Photomedicine (Phypers & Hanna 2025).

Ovarian PRP for Ovarian Rejuvenation

Ovarian PRP uses Platelet Rich Plasma (PRP) from a sample of the patient’s own blood. A small sample of the patient’s blood plasma is injected into the ovaries under mild sedation. It is a short process carried out by expert gynaecologists in our Harley Street Fertility Clinic and clinical studies show positive results for improving ovarian function.

Ovarian PRP intends to rejuvenate ovarian tissue, stimulate vascularisation, improve blood supply and re-awake dormant eggs into maturation for development within the ovary. Uterine PRP has shown to increase the depth of the uterine lining, with clinical studies already supporting this methodology.

Hyperbaric Oxygen Therapy (HBOT) for Fertility

Hyperbaric Oxygen Therapy (HBOT) is a supportive therapy to improve reproductive health outcomes for men and women. By delivering high concentrations of oxygen under gentle pressure (1.3 – 1.5 ATA), HBOT for Fertility may help improve circulation, cellular energy production, tissue repair, and oxygen delivery to the testes, ovaries and endometrium — areas critical for healthy reproductive function.

Hyperbaric Oxygen Therapy (HBOT) involves breathing concentrated oxygen inside a pressurised chamber, increasing the amount of oxygen dissolved within the blood and delivered to tissues throughout the body. Researchers are now investigating whether improved oxygenation may help support ovarian function, egg quality, embryo development, and endometrial health.

Who can receive treatment

The optimum age to improve fertility outcomes from our Ovarian Rejuvenation Programme (ORP) is for people in the mature age group of 35-50, because reproductive cells are more likely to lack cellular energy from the ageing process. The Ovarian Rejuvenation Programme (ORP can improve the following:

Low ovarian reserve.
Poor egg quality.
Multiple implantation failures.
Miscarriage.
Hormonal imbalances.
Endometriosis and adenomyosis.
Painful periods (dysmenorrhoea).
Unexplained age-related infertility.

Ovarian Rejuvenation Programme London Schedule

The Ovarian Rejuvenation Programme (ORP) is recommended during the lead up to fertilisation, regardless of whether fertilisation is via natural conception or IVF. The ORP helps to prepares the body and reproductive organs, and create optimum conditions for conception to take place.

After the PRP and LLLT / HBOT treatments have been delivered over the 8 week period, we recommend further LLLT / HBOT treatments from Day 1 during the stimulation phase of an IVF egg retrieval cycle, or in the lead up to ovulation for a natural conception.

Fees

A guide to the Ovarian Rejuvenation Programme (ORP) fees as follows:

6 x LLLT Gigalaser sessions £1,500.
5 x Hyperbaric Oxygen Therapy (HBOT) sessions £950.
2 x Ovarian PRP treatments £2,600 (£1,300 per treatment – second treatment optional and as advised by gynaecologist).
- Additional fees related to PRP treatment:
- Initial Consultation – £150 This is the starting point, where you’ll meet with the doctor to discuss suitability and next steps.
- PRP Treatment – £1,300. Includes sedation and injection into both ovaries.
- Female Screening Blood Tests – £250. Required prior to PRP. These include: FBC, HIV, Hep B surface antigen, Hep B core antibodies, Hep C antibodies, Rubella, Chlamydia, Gonorrhoea, HVS.
- Ultrasound Scans – £200 each. Scans are additional to the PRP fee. The need for scans before or after treatment is determined during your consultation, based on individual requirements.
- Follow-Up Consultation – £190 (optional but recommended).(There are additional costs for blood tests and scans prior to the Ovarian PRP procedure).
For more information on further additional sessions please refer to our Fees.