At Laser Medicine, London, we support the work of leading clinical fertility clinics around the world, with the application of Low Level Laser Light Therapy (LLLT), which is recognised to help improve fertility outcomes during the process of IVF or natural conception. Forward thinking IVF clinics in the UK, Europe and internationally, often suggest patients receive experimental procedures such as Ovarian PRP (Platelet Rich Plasma), to help rejuvenate ovaries and restore / improve ovarian function.
For several years we worked with Serum IVF Clinic in Athens, Greece, an early adopter of the Ovarian PRP procedure to support fertility outcomes during IVF. Since October 2023 we partner with specialist fertility gynaecologists at leading fertility clinics in London Harley Street, who carry the licence to carry out Ovarian PRP and Uterine PRP procedures in the UK. Together we continually monitor and assess improved fertility outcomes, which often present as an increase in ovarian follicles, a rise in AMH levels, and a drop in FSH.
We deliver Low Level Laser Light Therapy (Red Light Therapy) in combination with Ovarian PRP for Ovarian Rejuvenation, and LLLT with Uterine PRP to improve tissue integrity and thickness of the uterine lining. A combination of Ovarian PRP and / or Low Level Laser Therapy for Fertility can promote good reproductive health and improve egg quality for women who show signs of unspecified age-related infertility or premature ovarian failure. The treatment is also beneficial for PCOS and endometriosis, both factors for infertility. Many cases result in healthy live births after several years of failure to conceive, usually from unspecified age-related infertility or similar. We refer to this combined protocol in our Ovarian Rejuvenation Programme (ORP).
Please find more information on our Ovarian Rejuvenation Programme.
Ovarian PRP to improve fertility.
Ovarian PRP and Uterine PRP use platelets from the individual’s blood, which are injected into the patient’s ovaries and / or uterine tissue. The procedure for Ovarian PRP is carried out under mild sedation. There are a number of clinical studies relating to the efficacy of Ovarian and Uterine PRP to support fertility outcomes. A brief summary of clinical work in the field follows:
Ovarian PRP:
Intraovarian Platelet-Rich Plasma Injections: Safety and Thoughts on Efficacy Based on a Single Centre Experience With 469 Women (2023). PRP intraovarian injections associated with improved ovarian tissue and function.
Autologous Platelet-Rich Plasma Treatment Enables Pregnancy for a Woman in Premature Menopause (2018). A case study of one woman who experienced a biochemical pregnancy in menopause followed by a spontaneous abortion at week 5.
Ovarian rejuvenation and folliculogenesis reactivation in peri-menopausal women after autologous platelet-rich plasma treatment (2016). Successful temporary ovarian activity restoration in peri-menopausal women after an autologous Ovarian PRP treatment.
Uterine PRP:
Autologous platelet-rich plasma promotes endometrial growth and improves pregnancy outcome during in vitro fertilization
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8769175/ (2015). Platelet rich plasma was able to promote the endometrial growth and improve pregnancy outcomes of patients with thin endometrium.
Autologous platelet-rich plasma optimizes endometrial thickness and pregnancy outcomes in women with refractory thin endometrium of varied aetiology during fresh and frozen-thawed embryo transfer cycles (2021). PRP enhanced endometrial thickness significantly during fresh and FET cycles in thin endometrium.
PRP (Platelet Rich Plasma) Therapy is an experimental treatment to support IVF.
Ovarian PRP is a newly pioneered experimental procedure, which may offer hope to women with early premature ovarian failure, diminished ovarian reserve and to those who are advanced in reproductive age, or have had repeated IVF failure or poor egg quality. The studies identified above indicate the rejuvenation of ovarian tissue, a stimulation of increased vascularisation, improved blood supply and the re-awakening of dormant eggs into maturation for development within the ovary.
We recommend a combination of Ovarian PRP with Low Level Laser Therapy for fertility, to optimise increased vascularity within the ovaries with improved mitochondrial energy in the eggs.
Low Level Laser Therapy / PBMT as an ancillary IVF treatment.
Low Level Laser Therapy is also known as Red Light Therapy (because of the wavelengths used within the Infrared / Near Infrared range (600-1000nm)). Laser Therapy, also known as Red Light Therapy or Photobiomodulation Therapy (PBMT) has proven successful in various clinics worldwide as an IVF ancillary treatment. Success rates have proved as high as 65% for patients who have failed to fall pregnant many times before using various methods of TTC. Furthermore, laboratory studies have repeatedly shown the effectiveness of Low Level Laser Therapy for Fertility due to enhanced mitochondrial activity and ATP production, increased blood flow and the reduction of oxidative damage, promoting the energetic value of the developing embryo in early stages. At our Harley Street fertility clinic, we continue to monitor and celebrate the positive effects of photobiomodulation for reproductive health and fertility.
Please visit our Services page to find out about a Laser Medicine course of treatments in Low Level Laser for Fertility.
LLLT Courses to Improve Egg Quality
The optimum age for promoting fertilisation via LLLT is for women in the mature age group of 35-50, because reproductive cells are more likely to lack cellular energy as a result of the ageing process.
Low Level Laser Therapy (LLLT) is recommended as an IVF ancillary treatment, during the lead up to a fertilisation, regardless of whether fertilisation is to be achieved via natural or ART/IVF methods. It prepares the body and reproductive organs, and promotes optimum conditions for conception to take place. In some cases we would recommend LLLT in combination with Ovarian PRP.
The overall general health and age of a patient determines the frequency of treatment, which is normally around 2-3 treatments every 6 weeks. During a period of trying to conceive (either via natural or IVF methods), we base our protocols around a schedule of 6 treatments over a period of 2 weeks from Day 1 to Day 14 of the cycle, and if conception does not take place, to repeat the following month.
About Laser Medicine
Laser Medicine is a member of the following professional bodies:
- British Medical Laser Association (BMLA).
- Complementary Medical Association (CMA).
For more information on the Laser Medicine London, Harley Street Fertility Clinic and our Laser Therapy for Fertility Services.
To talk to us directly and discuss how PBMT or Low Level Laser may be suitable for you, please Contact Us.
